Research Use Only · In-Vitro
Peptide Storage and Stability
By Peptide Information · Updated June 14, 2025
21 CFR § 809.10(c)(2)(i)
Corepepti emphasizes controlled storage practices to preserve the structural integrity, purity, and stability of research-grade peptides intended exclusively for in-vitro laboratory applications. Proper handling reduces degradation, oxidation, and experimental variability.
Storage Best Practices
- Short-term: refrigerate at ~4 °C (39 °F); lyophilized peptides remain stable but refrigeration is preferred.
- Long-term: store at −80 °C (−112 °F) for optimal stability.
- Avoid freeze–thaw cycles; aliquot samples to prevent repeated exposure.
- Avoid frost-free freezers due to temperature fluctuations.
Preventing Oxidation & Moisture Exposure
- Allow vials to reach room temperature before opening.
- Keep containers tightly sealed and limit exposure to air.
- Use dry inert gas (nitrogen or argon) when possible.
- Peptides containing C, M, or W residues are more oxidation-sensitive.
- Aliquot to minimize handling and contamination.
Storage of Peptides in Solution
- Solutions have shorter stability and increased microbial susceptibility.
- Use sterile research buffers at pH 5–6.
- Aliquot solutions to avoid freeze–thaw cycling.
- Store at 4 °C for up to 30 days; freeze at −80 °C for long-term storage.
Choosing Storage Containers
- Use airtight, chemically inert containers.
- Glass vials offer superior inertness; polypropylene provides durability.
- Peptides may ship in plastic but can be transferred to glass for long-term storage.
Key Takeaways
- Store peptides in cold, dry, dark environments.
- Avoid repeated freeze–thaw cycles.
- Minimize air and light exposure.
- Avoid long-term storage in solution.
- Aliquot samples to match experimental requirements.
These guidelines apply exclusively to in-vitro laboratory research. Corepepti compounds are not approved for human or veterinary use. Users are responsible for lawful handling and adherence to applicable laboratory and safety regulations.
